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eszopiclone
(e ZOP i klone)

What is eszopiclone?
Eszopiclone is a sedative, also called a hypnotic. It affects chemicals in your brain that may become unbalanced and cause sleep problems (insomnia). Eszopiclone is used to treat insomnia. This medication causes relaxation to help you fall asleep and stay asleep. Eszopiclone may also be used for purposes other than those listed in this medication guide.

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What is the price of this medication and similar alternatives?

This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.

Lunesta 1MG Tablets SEPRACOR PHARMACEUTICALS30/$164.81 or 90/$484.36
Lunesta 2MG Tablets SEPRACOR PHARMACEUTICALS30/$168.77 or 90/$495.5
Lunesta 3MG Tablets SEPRACOR PHARMACEUTICALS30/$168.78 or 90/$482.27

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What are the possible side effects of eszopiclone?

Eszopiclone may cause a severe allergic reaction. Stop taking eszopiclone and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using eszopiclone and call your doctor at once if you have any of these serious side effects:

  • aggression, agitation, changes in behavior;

  • thoughts of hurting yourself; or

  • hallucinations (hearing or seeing things).

Less serious side effects may include:

  • day-time drowsiness, dizziness, "hangover" feeling;

  • problems with memory or concentration;

  • anxiety, depression, nervous feeling;

  • headache;

  • nausea, stomach pain, loss of appetite, constipation;

  • dry mouth;

  • unusual or unpleasant taste in your mouth; or

  • mild skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.

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How should I take eszopiclone?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label. Take eszopiclone only if you are able to get a full night's sleep before you must be active again. Never take this medication during your normal waking hours, unless you have at least 8 hours to dedicate to sleeping. Take eszopiclone with a full glass of water. Avoid taking eszopiclone within 1 hour after eating a high-fat or heavy meal. This will make it harder for your body to absorb the medication.

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What is the most important information I should know about eszopiclone?
Eszopiclone may cause a severe allergic reaction. Stop taking eszopiclone and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Eszopiclone will make you fall asleep. Never take this medication during your normal waking hours, unless you have at least 8 hours to dedicate to sleeping. Some people using this medicine have engaged in activity such as driving, eating, or making phone calls and later having no memory of the activity. If this happens to you, stop taking eszopiclone and talk with your doctor about another treatment for your sleep disorder.

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What happens if I miss a dose?
Since eszopiclone is usually taken as needed, you may not be on a dosing schedule. Never take this medication if you do not have at least 8 hours to sleep before being active again. Do not take extra medicine to make up a missed dose.

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What other drugs will affect eszopiclone?
Before taking eszopiclone, tell your doctor if you are taking any of the following drugs: rifampin (Rifadin, Rifater, Rifamate, Rimactane); ketoconazole (Nizoral); or antidepressants, narcotic pain medications, muscle relaxers, seizure medications, or anti-anxiety medications. This list is not complete an there may be other drugs that can interact with eszopiclone. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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Can I take this if I am pregnant or trying to get pregnant or if I am breastfeeding?

Eszopiclone has been assigned to pregnancy category C by the FDA. Animal studies have revealed evidence of slight reductions in fetal weight and evidence of developmental delay at maternally toxic doses. Increased post-implantation loss, decreased postnatal pup weights and survival, and increased pup startle response were reported to occur at all doses. There are no controlled data in human pregnancy. Eszopiclone should only be given during pregnancy when benefits outweigh risks.

Animal studies have reported decreased fertility thought to be due to effects in both males and females. No females became pregnant when both males and females where treated with the highest doses. Other effects have been reported to include pre-implantation loss, abnormal estrus cycles, decreases in sperm number and motility, and increases in morphologically abnormal sperm.

There are no data on the excretion of eszopiclone into human milk. Because many drugs are excreted into human milk caution is recommended if eszopiclone is administered to a nursing woman.

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Who should NOT use this medication?

  • None known.

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What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an eszopiclone overdose are not known.

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What should I discuss with my healthcare provider before taking eszopiclone?
Eszopiclone will make you fall asleep. Never take this medication during your normal waking hours, unless you have at least 8 hours to dedicate to sleeping. Some people using this medicine have engaged in activity such as driving, eating, or making phone calls and later having no memory of the activity. If this happens to you, stop taking eszopiclone and talk with your doctor about another treatment for your sleep disorder. Do not use this medication if you are allergic to eszopiclone.

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Can I stop taking the medication if I feel better?
As a general rule, you should always take your medications exactly as prescribed and do not change the dosage or stop taking the medication without first discussing it with your healthcare provider.

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I am on so many medications; do I have to take them all?
This is called polypharmacy—many different medications being used at the same time by one person. Sometimes, being on multiple medications is acceptable and appropriate but at other times it may be problematic. If you are receiving your medications from multiple physicians you need to ensure that they all know what medications you are taking. The best way to do this is to make a list of all the medications you are currently using, including all nutritional supplements, homeopathic remedies, vitamins and over-the-counter drugs (if possible, also include all the diseases you have been diagnosed with). Give a copy to every doctor who takes care of you so they have it on file, this way they can avoid duplicating medications and perhaps even try to consolidate some. After every doctor's visit remember to update the list accordingly. Also, as much as you possibly can, try to use the same pharmacy to fill all your prescriptions, this way any potential drug interactions can be caught and averted.

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Where can I get more information?
More Information

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