Stages of Non-Small Cell Lung... Health Article

Doctors need to know which stage your lung cancer is in to help decide what treatment to recommend. The stage is based on these things.

• Size and extent of your tumor

• Whether there are lymph nodes involved and, if so, how many

• Whether the cancer has spread to other parts of the body

Your oncologist gets this information from doing tests, such as CT scans.

The stages of non-small lung cancer are described using the TNM System.

The TNM System

The TNM System is a standard system for describing the extent of a cancer’s growth. Here’s what the letters stand for in the TNM System.

• T tells how large a tumor is.

• N tells whether the lymph nodes near the tumor are cancerous.

• M tells whether the cancer has spread (metastasized) to other organs in the body, such as your brain, bones, or liver.

Once your oncologist has determined your T, N, and M stages, this information is put together in a stage grouping. Numerical values, from X to 3, are assigned to each of the T, N, and M categories. Stage grouping is used to determine your overall disease stage.

Stage Groupings

These are the stages of non-small cell lung cancer. Each TNM category, with its assigned numerical value from X to 3, falls into one of these stages.

• Occult. This means that there are cancer cells in your sputum, which is mucus from the lungs. At this stage, the tumor in your lungs cannot be seen. You may hear your doctor use these TNM terms for this stage: TX, N0, M0.

• Stage 0. In this stage, cancer is only in the cells lining your air passages. The cancer is very tiny. It has not spread. Cancer at this stage is also called carcinoma in situ. You may hear your doctor use these TNM terms for this stage: Tis, NO, MO.

• Stage I. In this stage, there is cancer in your lung, and it may affect your bronchi or the lining outside your lung. Cancer found at this stage offers the best chance of survival. You may hear your doctor use these TNM terms for this stage: T1, N0, M0. Stage I is divided into Stage IA and IB based on the size of the tumor. For Stage I, your doctor may use these TNM terms: T1, N0, M0. For Stage IB, your doctor may use these TNM terms: T2, N0, M0.

• Stage II. In this stage, the cancer has spread into surrounding tissue, and there is cancer in your lymph nodes within your lung on the same side the cancer is in. The tumor may be operable but may not be able to be completely removed. The chance of survival is good at this stage. You may hear your doctor use these TNM terms for this stage: T2, N1, MO. Stage II is divided into Stage IIA and IIB based on the size of the tumor and whether it has spread to the lymph nodes. For Stage IIA, your doctor may use these TNM terms: T1, N1, M0. For Stage IIB, your doctor may use these TNM terms: T2, N1, M0 or T3, N0, M0.

• Stage III. Stage III is divided into 2 sub-stages: Stage IIIA and Stage IIIB. In Stage IIIA, the cancer has spread to the lymph nodes in the middle of the chest, called the mediastinum, on the same side as the cancer. It may also have spread to lymph nodes behind your windpipe, called the trachea. For Stage IIIA, you may hear your doctor use these TNM terms: T1, N2, M0 or T2, N2, M0 or T3, N1, M0 or T3, N2, M0. In Stage IIIB, the cancer has spread to the lymph nodes above your collarbone on either side or to the lymph nodes on the other side of your chest. The tumor will likely not be able to be completely removed by surgery. For Stage IIIB, you may hear your doctor use these TNM terms: Any T, N3, M0 or T4, any N, M0.

• Stage IV. In Stage IV, the cancer has spread to other organs in your body. The tumor cannot be operated on. You may hear your doctor use these TNM terms for this stage: any T, any N, M1.