Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking trandolapril. Drink plenty of water each day while you are taking this medication.

What is trandolapril?

Trandolapril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme.

Trandolapril is used to treat high blood pressure (hypertension), and to improve survival after a heart attack.

Trandolapril may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking trandolapril?

Before using trandolapril, tell your doctor if you are allergic to any drugs, or if you have:

• kidney disease (or if you are on dialysis);

• liver disease;

• heart disease or congestive heart failure;

• diabetes; or

• a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis.

If you have any of these conditions, you may not be able to use trandolapril, or you may need a dosage adjustment or special tests during treatment.

Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Trandolapril could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Trandolapril can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

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