What is the most important information I should know about tacrolimus?
Taking tacrolimus may increase your risk of developing certain types of cancer, especially
skin cancer. The risk may be higher in people who are treated over long periods of time with
drugs that weaken the immune system. Talk with your doctor about your individual risk.
Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Use a
sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.
There are many other medicines that can interact with tacrolimus. Tell your doctor about all the prescription and over-the-counter medications you use. This
includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start
using a new medication without telling your doctor. Keep a list with you of all the medicines you
use and show this list to any doctor or other healthcare provider who treats you.
Do not consume grapefruit or grapefruit juice during treatment with tacrolimus
unless your doctor has told you do. Tacrolimus can have a dangerous interaction with grapefruit
or grapefruit juice.
Tacrolimus can lower the blood cells that help your body fight infections. This can make
it easier for you to bleed from an injury or get sick from being around others who are ill. To be
sure your blood cells do not get too low, your blood will need to be tested on a regular basis.
Your kidney or liver function may also need to be tested. Do not miss any scheduled
appointments.
Some people receiving tacrolimus after a kidney transplant have developed diabetes, most
often in people who are Hispanic or African-American. Talk with your doctor about your
individual risk of diabetes.
What is tacrolimus?
Tacrolimus lowers your body's immune system. The immune system helps your body
fight infections. The immune system can also fight or "reject" a transplanted organ such as a
liver or kidney. This is because the immune system treats the new organ as an invader.
Tacrolimus is used together with other medicines to prevent your body from rejecting a
heart, liver, or kidney transplant.
Tacrolimus may also be used for other purposes not listed in this medication guide.
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Medicare's drug plans are subsidized by the US federal government and offered through insurers.
