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What is the most important information I should know about sulfisoxazole?

Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Sulfisoxazole will not treat a viral infection such as the common cold or flu. Do not give this medication to another person, even if they have the same symptoms you do.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

What is sulfisoxazole?

Sulfisoxazole is a sulfonamide ("sulfa") antibiotic that helps keep bacteria from growing in your body.

Sulfisoxazole is used to treat or prevent many different types of infections caused by bacteria, such as bladder infections, ear infections, or meningitis.

Sulfisoxazole may also be used for other purposes not listed in this medication guide.

What should I discuss with my health care provider before taking sulfisoxazole?

Do not use this medication if you are allergic to sulfisoxazole or to any other sulfa drugs such as Azulfidine, Bactrim, Cotrim, Septra, or Sulfazine. Women who are in late pregnancy or are breast-feeding should not take sulfisoxazole.

Before using sulfisoxazole, tell your doctor if you are allergic to any drugs, or if you have:

• asthma;

• diabetes;

• liver disease;

• kidney disease;

• anemia (a lack of red blood cells);

• a condition called G6PD (glucose-6-phosphate dehydrogenase) deficiency;

• a history of any type of allergy; or

• if you are unable to urinate.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take sulfisoxazole.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Sulfisoxazole can cause jaundice (yellowing of the skin or eyes) and other problems in a newborn if the mother has taken this medication late in pregnancy, Tell your doctor if you are pregnant or plan to become pregnant during treatment with sulfisoxazole. Sulfisoxazole can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby, especially if the baby is younger than 2 months old. Do not give this medicine to a child younger than 2 months old without the advice of a doctor.