What is the most important information I should know about Rho(D) IG?
While you are being treated with this medication, call your doctor right away if you
have
fever, chills, shaking,
back pain, a change in the color of your urine or how much you
urinate, sudden
weight gain, or swelling in your hands, ankles, or feet.
Do not receive live-virus
vaccines such as
measles,
mumps,
rubella, or
chicken pox
(also called
MMR or
Varivax) for at least 3 months after treatment with Rho(D) IG. These
vaccines may not work properly during Rho(D) IG treatment and shortly afterward.
Rho(D) IG is made from human plasma (part of the blood) and may contain viruses and
other infectious agents that can cause disease. Although Rho(D) IG is screened, tested, and
treated to reduce the risk of it containing anything that could cause disease, there is still a small
possibility it could transmit disease. Talk with your doctor about the risks and benefits of using
this medication.
If you are an Rh-negative woman and you become pregnant, you must tell
your doctor if you have ever been exposed to Rh-positive blood in your lifetime.
This includes exposure from a mismatched blood transfusion, or exposure during your first
pregnancy. Your history of exposure and treatment will be extremely important to each and
every one of your pregnancies.
What is Rho(D) IG?
Rho(D) immune globulin (Rho(D) IG) is a sterilized solution made from human blood.
Rh is a substance that most people have in their blood (Rh positive) but some people don't (Rh
negative). A person who is Rh negative can be exposed to Rh positive blood through a
mismatched blood transfusion or during pregnancy when the baby has the opposite blood type.
When this exposure happens, the Rh negative blood will respond by making antibodies that will
try to destroy the Rh positive blood cells. This can cause medical problems such as anemia (loss
of red blood cells), kidney failure, or shock.
Rho(D) IG is used to prevent an immune response to Rh positive blood in people with an
Rh negative blood type. Rho(D) IG may also be used in the treatment of immune
thrombocytopenic purpura (ITP).
Rho(D) IG may also be used for other purposes not listed in this medication guide.
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