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What is the most important information I should know about prochlorperazine?

Call your doctor immediately if you have uncontrollable movements of the mouth, tongue, cheeks, jaw, arms, or legs. Use caution when driving, operating machinery, or performing other hazardous activities. Prochlorperazine may cause dizziness, drowsiness, or blurred vision. If you experience dizziness, drowsiness or blurred vision, avoid these activities. Dizziness is likely to occur when you are rising from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking prochlorperazine. Do not crush, break, or chew any sustained-release capsules or tablets. Swallow them whole.

Do not let the liquid form of prochlorperazine touch your skin or clothes.

Do not mix the liquid form with coffee, cola, tea, grape, or apple juice.

What is prochlorperazine?

Prochlorperazine is in a class of drugs called phenothiazines.

Prochlorperazine is most commonly used to treat nausea and vomiting. It is also sometimes used to treat psychotic disorders and anxiety.

Prochlorperazine may also be used for purposes other than those listed in this medication guide.

Who should not take prochlorperazine?

Before taking this medication, tell your doctor if you have

• a bone marrow disease,

• glaucoma,

• seizures,

• Parkinson's disease,

• kidney disease,
• liver disease, or

• an enlarged prostate.

You may not be able to take prochlorperazine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

It is not known whether prochlorperazine will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. It is not known whether prochlorperazine will harm a nursing infant. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. If you are over 60 years of age, you may be more likely to experience side effects from prochlorperazine. You may require a lower dose of this medication.