What is the most important information I should know about pegvisomant?
The stopper on the vial of Somavert contains latex. Do not use this product without first
talking to your doctor if you are allergic to latex.
Your doctor will want you to have blood tests and/or other medical evaluations during treatment
with pegvisomant to monitor progress and side effects. It is especially important to monitor liver
function and insulin-like growth factor (IGF-I) with regularly scheduled blood tests.
What is pegvisomant?
Pegvisomant is a manufactured protein similar to human growth hormone (GH). Pegvisomant
binds to the same receptor in the body as growth hormone, and blocks the effects of growth hormone.
Pegvisomant is used for the treatment of acromegaly (a growth disorder caused by too much
growth hormone).
Pegvisomant may also be used for purposes other than those listed here.
What should I discuss with my health care provider before taking pegvisomant?
Before taking pegvisomant, tell your doctor if you
-
have an allergy to pegvisomant, another growth hormone product,
or latex (the stopper on the vial of Somavert contains latex);
-
have a tumor that secretes growth hormone;
-
have diabetes;
-
have liver problems; or
-
are taking a narcotic pain or cough medication such as
codeine (Tylenol #3, others), hydrocodone (Vicodin, Lorcet, others), oxycodone (Percocet,
others), morphine (MS Contin, MSIR, OxyContin, others), fentanyl (Duragesic, others), and
others.
You may not be able to take pegvisomant or you may require a dosage
adjustment or special monitoring during treatment.
Pegvisomant is in the FDA pregnancy category B. This means that pegvisomant is not
expected to be harmful to an unborn baby. Do not take pegvisomant without first talking to your doctor
if you are
pregnant or could become pregnant during treatment.
It is not known whether pegvisomant passes into breast milk. Do not take pegvisomant
without first talking to your doctor if you are
breast-feeding a baby.
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