What is the most important information I should know about metformin and rosiglitazone?
Do not use
metformin and
rosiglitazone if you have
kidney disease, or if you are in a
state of
diabetic ketoacidosis (call your doctor for treatment with
insulin).
Before taking metformin and rosiglitazone, tell your doctor if you have congestive heart
failure or heart disease, a history of heart attack or stroke, liver disease, or eye problems caused
by diabetes.
Some people have developed a life-threatening condition called
lactic acidosis while
taking metformin and rosiglitazone.
Get emergency medical help if you have any of
these symptoms of lactic acidosis: weakness, increasing sleepiness, slow heart rate,
cold feeling, muscle pain, shortness of breath, stomach pain, feeling light-headed, and fainting.
What is metformin and rosiglitazone?
Metformin and rosiglitazone is a combination of two oral diabetes medicines that help
control blood sugar levels.
Metformin and rosiglitazone is for people with type 2 diabetes who do not use daily
insulin injections. This medication is not for treating type 1 diabetes.
Metformin and rosiglitazone may also be used for other purposes not listed in this
medication guide.
What should I discuss with my healthcare provider before taking metformin and rosiglitazone?
Some people have developed a life-threatening condition called lactic acidosis while
taking metformin and rosiglitazone. Get emergency medical help if you have any of
these symptoms of lactic acidosis: weakness, increasing sleepiness, slow heart rate,
cold feeling, muscle pain, shortness of breath, stomach pain, feeling light-headed, and fainting.
Do not use metformin and rosiglitazone if you have kidney disease, or if you are in a
state of diabetic ketoacidosis (call your doctor for treatment with insulin).
Before taking this medication, tell your doctor if you have congestive heart failure or heart
disease, a history of heart attack or stroke, liver disease, or eye problems caused by diabetes.
Some women using metformin and rosiglitazone have started having menstrual
periods, even after not having a period for a long time due to a medical condition. You may be
able to get pregnant if your periods restart. Talk with your doctor about the need for birth
control.
Women may also be more likely than men to have bone fractures in the upper arm,
hand, or foot while taking metformin and rosiglitazone. Talk with your doctor if you are
concerned about this possibility.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell
your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether metformin and rosiglitazone passes into breast milk or if it
could harm a nursing baby. Do not take metformin and rosiglitazone without first talking to your
doctor if you are breast-feeding a baby.
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