What is the most important information I should know about mesoridazine?
In rare cases, mesoridazine has caused serious irregular heartbeats, sometimes
resulting in death. Do not take mesoridazine if you have any of the following conditions or a
history of these conditions:
heart disease; an
irregular heartbeat or a history of irregular
heartbeats; a history of prolonged QT intervals; a
family history of congenital
long QT
syndrome;
hypokalemia (low levels of
potassium in your blood); slow heartbeats that require
treatment; or other heartbeat disturbances. These conditions may increase the risk of irregular
heartbeats,
heart attack, and death while taking mesoridazine.
Do not take mesoridazine with other drugs that can affect heartbeat rhythms such as
quinidine (Cardioquin, Quinaglute, Quinidex, others),
procainamide (Procan,
Procanbid,
Pronestyl),
disopyramide (Norpace), and others. Taken with any of these drugs, mesoridazine
(Serentil) may cause irregular heartbeats that could lead to death. This is not a complete list of
drugs that may interact with mesoridazine and cause heart problems. Talk to your doctor or
pharmacist before taking any other prescription or over-the-counter medications.
Call your doctor immediately if you have uncontrollable movements of the mouth,
tongue, cheeks, jaw, arms, or legs;
fever; muscle rigidity; sweating; irregular pulse; or fast or
irregular heartbeats.
Use caution when driving, operating machinery, or performing other hazardous
activities. Mesoridazine may cause dizziness or drowsiness. If you experience dizziness or
drowsiness, avoid these activities.
Dizziness may be more likely to occur when you rise from a sitting or lying position. Rise
slowly to prevent dizziness and a possible fall.
Mesoridazine may interact with other drugs that cause drowsiness, including alcohol,
antidepressants,
antihistamines, pain relievers,
anxiety medicines,
seizure medicines, and
muscle
relaxants. Dangerous
sedation, dizziness, or drowsiness may occur if mesoridazine is taken with
alcohol or any of these medications. Talk to your doctor before taking mesoridazine in
combination with alcohol or any other prescription or over-the-counter medicines.
Do not mix the liquid form of this medication with coffee, cola, or tea.
What is mesoridazine?
Mesoridazine is in a class of drugs called phenothiazines. It works by changing the
actions of chemicals in your brain.
Mesoridazine is used to treat schizophrenia.
Mesoridazine may also be used for purposes other than those listed in this medication
guide.
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