.
Do not use if you are pregnant. Use effective birth control, and tell your doctor if you become pregnant during
treatment.
You should not use this medication if you are allergic to leuprolide or similar
medications such as buserelin (Suprefact, Suprecor), goserelin (Zoladex), histrelin (Supprelin),
nafarelin (Synarel), or if you have abnormal vaginal bleeding that has not been diagnosed by a
doctor; or if you are breast-feeding a baby.
Before using leuprolide, tell your doctor if you have epilepsy, asthma, migraines, heart or
kidney disease, a history of depression, bone cancer affecting your spine, blood in your urine, or
if you are unable to urinate.
Tell your doctor if you have a personal or family history of osteoporosis, or if you have
any risk factors for bone loss such as smoking, alcohol use, or taking steroid or seizure
medications long term. Long-term use of this medication may decrease bone density, possibly
leading to osteoporosis.
Certain brands or strengths of leuprolide are used to treat only men and should not be
used in women or children. Always check your medication to make sure you have received the
correct brand and strength prescribed by your doctor.
What is leuprolide?
Leuprolide is a man-made form of a hormone that regulates many processes in the body.
Leuprolide overstimulates the body's own production of certain hormones, which causes that
production to shut down temporarily. Leuprolide reduces the amount of testosterone in men or
estrogen in women.
Leuprolide is used in men to treat the symptoms of prostate cancer.
Leuprolide treats only the symptoms of prostate cancer and does not treat the cancer itself. Use
any other medications your doctor has prescribed to best treat your condition.
Leuprolide is used in women to treat symptoms of endometriosis
(overgrowth of uterine lining outside of the uterus) or uterine fibroids.
Leuprolide is also used to treat precocious (early-onset) puberty in both male and female
children.
Leuprolide may also be used for other purposes not listed in this medication guide.
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