What is the most important information I should know about isoniazid and rifampin?
Take all of the
isoniazid and
rifampin that has been prescribed for you even if you
begin to feel better. Your symptoms may begin to improve before the
infection is completely
treated.
Avoid alcohol while taking isoniazid and rifampin. Alcohol will increase the risk of
damage to your liver during treatment with this medication.
Call your doctor immediately if you experience a fever, chills, a sore throat, muscle and
bone pain, a headache, excessive tiredness or weakness, numbness or tingling in your hands or
feet, loss of appetite, nausea and vomiting, yellowing of your skin or eyes, darkening of your
urine, unusual bleeding or bruising, a rash, or itching.
Take isoniazid and rifampin on an empty
stomach 1 hour before or 2 hours after a
meal.
This medication may decrease the effectiveness of
birth control pills. Talk to your
doctor about using another form of birth control during treatment.
What is isoniazid and rifampin?
Isoniazid and rifampin are antibiotics. They prevent tuberculous bacteria from
multiplying in your body.
Isoniazid and rifampin are used together to treat tuberculosis (TB).
Isoniazid and rifampin may also be used for purposes other than those listed in this
medication guide.
Who should not take isoniazid and rifampin?
Before taking this medication, tell your doctor if you have
You may not be able to take isoniazid and rifampin, or you may
require a lower dose or special monitoring during treatment if you have any of the conditions
listed above.
It is not known whether isoniazid and rifampin will harm an unborn baby. Do not
take this medication without first talking to your doctor if you are
pregnant.
It is also not known whether isoniazid and rifampin will harm a nursing baby. Do not
take this medication without first talking to your doctor if you are
breast-feeding a baby.