Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.
Do not use ibuprofen and pseudoephedrine if you have used an MAO inhibitor such
as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl,
Emsam), or tranylcypromine (Parnate) within the past 14 days.
Ibuprofen can increase your risk of life-threatening heart or circulation problems,
including heart attack or stroke. Do not use this medicine just before or after having heart bypass
surgery (also called coronary artery bypass graft, or CABG).
Seek emergency medical help if you have symptoms of heart or circulation problems,
such as chest pain, weakness, shortness of breath, slurred speech, or problems with vision or
balance.
Ibuprofen can also increase your risk of serious effects on the stomach or intestines,
including bleeding or perforation (forming of a hole). These conditions can be fatal and can
occur without warning at any time while you are taking ibuprofen.
Call your doctor at once if you have symptoms of bleeding in your stomach or intestines.
This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee
grounds.
Do not take more of this medication than is recommended. An overdose of ibuprofen
can cause damage to your stomach or intestines.
What is ibuprofen and pseudoephedrine?
Ibuprofen is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs).
Ibuprofen works by reducing hormones that cause inflammation and pain in the body.
Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages.
Dilated blood vessels can cause nasal congestion (stuffy nose).
The combination of ibuprofen and pseudoephedrine is used to treat stuffy nose, sinus
congestion, cough, and pain or fever caused by the common cold or flu.
Ibuprofen and pseudoephedrine may also be used for other purposes not listed in this
medication guide.
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