What is the most important information I should know about goserelin?
Goserelin may cause decreased bone mineral density with prolonged use. Smoking, frequent
alcohol use, family history of osteoporosis, and the use of certain medications may increase the risk of
bone loss. Talk to your doctor about the risk of decreased bone mineral density.
Initially, goserelin may cause symptoms of your condition to worsen temporarily. Contact your
doctor if symptoms do not improve within several weeks of starting treatment.
If you are a pre-menopausal female, notify your doctor if your menstrual period continues to
occur. Goserelin usually stops menstruation. Delayed or missed doses of goserelin may cause ovulation
or menstrual bleeding. Following treatment with goserelin, there may be a delay before the return of
regular menstrual periods. Check with your doctor if your period does not restart within a few months
of ending treatment.
Do not take goserelin if you are
pregnant or could become pregnant
during treatment. Goserelin is known to be harmful to an unborn baby. A nonhormonal method of
birth
control must be used during treatment with goserelin to ensure prevention of pregnancy. Although
goserelin may stop ovulation and menstruation, a nonhormonal method of birth control must also be
used. If a dose of goserelin is missed or delayed, ovulation and/or
breakthrough bleeding may occur. A
nonhormonal method of birth control must also be used until the return of menstruation or for at least 12
weeks following treatment with goserelin.
What is goserelin?
Goserelin is a man-made protein that is like a hormone in the body called
gonadotropin-releasing hormone (GnRH). Goserelin decreases levels of testosterone in men and
estrogen in women.
Goserelin is used in the treatment of endometriosis, to thin the endometrial layer (lining of the
uterus) prior to surgery for abnormal uterine bleeding, and some types of prostate and breast cancer.
Goserelin may also be used for purposes other than those listed in this medication guide.
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