Drug Notebook

FDA Alerts

    Fluticasone Propionate in Fixed Combination with Salmeterol
  • Possible increase in asthma-related death in patients receiving long-acting β2-adrenergic bronchodilators, including salmeterol, in addition to usual asthma therapy.
  • Reserve use of fixed combination with salmeterol for patients with asthma whose disease is inadequately controlled with other asthma controller therapy (e.g., low to medium dosage of inhaled corticosteroids) or whose disease severity warrants treatment with 2 maintenance therapies. (See Acute Exacerbations of Asthma or COPD under Cautions).

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What is the most important information I should know about fluticasone inhalation?

Do not use fluticasone inhalation to treat an asthma attack that has already begun. It will not work fast enough to reverse your symptoms. Use another, faster-acting inhalation medication to treat an asthma attack.

Contact your doctor if your asthma symptoms do not improve after using fluticasone inhalation for 2 weeks.

Seek medical attention if you think any of your asthma medications are not working as well as usual. An increased need for medication could be an early sign of a serious asthma attack.

Your dosage needs may change if you have surgery, are ill, are under stress, or have recently had an asthma attack. Talk with your doctor if any of your asthma medications do not seem to work as well in treating or preventing asthma attacks.

If you were switched from an oral (taken by mouth) steroid to fluticasone inhalation, you may need to go back to taking the oral medicine if you are under stress or have an asthma attack or other medical emergency. Carry an identification card or wear a medical alert ID to let others know that you may need an oral steroid in an emergency.

What is fluticasone inhalation?

Fluticasone is a steroid. It prevents the release of substances in the body that cause inflammation.

Fluticasone inhalation is used to prevent asthma attacks. It will not treat an asthma attack that has already begun.

Fluticasone may also be used for other purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using fluticasone inhalation?

Before using this medication, tell your doctor if you have been sick or had an infection of any kind. You may not be able to use fluticasone inhalation until you are well.

FDA pregnancy category C. It is not known whether fluticasone inhalation is harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether fluticasone passes into breast milk or if it could harm a nursing baby. Do not use fluticasone inhalation without telling your doctor if you are breast-feeding a baby.

Fluticasone can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medication.

Do not give this medicine to a child younger than 4 years old without the advice of a doctor.

Long-term use of steroids may lead to bone loss (osteoporosis), especially if you smoke, if you do not exercise, if you do not get enough vitamin D or calcium in your diet, or if you have a family history of osteoporosis. Talk with your doctor about your risk of osteoporosis.

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