Do not use this medication if you have any of the following conditions: a history of
stroke or
This medication can cause birth defects in an unborn baby. Do not use
if you are pregnant. Use an effective form of birth control, and tell your doctor if you
become pregnant during treatment.
Estrogens will not prevent heart disease, heart attack, stroke, breast
cancer, or dementia, and may actually increase your risk of developing these conditions.
Estrogens may also increase your risk of uterine or ovarian cancer.
Talk with your doctor about your individual risks before using estradiol long-term. Your
doctor should check your progress on a regular basis (every 3 to 6 months) to determine whether
you should continue this treatment.
Have regular physical exams and self-examine your breasts for lumps on a monthly basis
while using estradiol topical.
What is estradiol topical?
Estradiol is a form of estrogen, a female sex hormone that regulates many processes in the
body.
Estradiol topical is used to treat certain symptoms of menopause such as hot flashes, and
vaginal dryness, burning, and irritation.
Estradiol topical may also be used for other purposes not listed in this medication guide.
What should I discuss with my health care provider before using estradiol topical?
Estrogens will not prevent heart disease, heart attack, stroke, breast
cancer, or dementia, and may actually increase your risk of developing these conditions.
Estrogens may also increase your risk of uterine or ovarian cancer.
Talk with your doctor about your individual risks before using estradiol long-term. Your
doctor should check your progress on a regular basis (every 3 to 6 months) to determine whether
you should continue this treatment.
You should not use estradiol topical if you have:
-
a bleeding or blood-clotting disorder;
-
liver or kidney disease;
-
a history of stroke or circulation problems;
-
abnormal vaginal bleeding that a doctor has not checked;
or
-
any type of breast, uterine, or hormone-dependent cancer.
If you have certain conditions, you may need a dose adjustment or
special tests to safely use this medication. Tell your doctor if you have:
FDA pregnancy category X. This medication can cause birth
defects. Do not use estradiol topical if you are pregnant. Tell your doctor
right away if you become pregnant during treatment. Use an effective form of birth control while
you are using this medication.
Estradiol can pass into breast milk and may harm a nursing baby. This medication
may also slow breast milk production. Do not use if you are breast-feeding a baby.
Estradiol increases your risk of developing endometrial hyperplasia, a condition that may
lead to cancer of the uterus. Taking progestins while using estradiol may lower this risk. If your
uterus has not been removed, your doctor may prescribe a progestin for you to take while you are
using estradiol topical.
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