Join Now | Sign in

Drug Notebook

Save

Generic Name: cisplatin

View All Brands

An alkylating agent - used in Bone Marrow Transplantation and Blood Cell Transplantation and treats ... more

FDA Alerts

Experience of Supervising Clinician

Use under supervision of a qualified clinician experienced in therapy with antineoplastic agents. Use only when adequate treatment facilities for appropriate management of therapy and complications are available.

Dose-Related Toxicities

Risk of dose-related toxicities, including myelosuppression, nausea, vomiting, and cumulative, severe renal toxicity. Dosages >100 mg/m²/cycle once every 3–4 weeks rarely used.

Ototoxicity

Risk of ototoxicity; more pronounced in children. Manifestations include tinnitus, loss of high frequency hearing, decreased hearing acuity, and, occasionally, deafness.

Anaphylaxis

Risk of anaphylactoid reactions (e.g., facial edema, bronchoconstriction, wheezing, tachycardia, hypotension); may occur within minutes following administration. (See Anaphylactoid Reactions under Cautions.) IV epinephrine, corticosteroids, and antihistamines have been effectively employed to alleviate symptoms.

Potential Medication Errors

Avoid accidental, potentially fatal, overdosage due to confusion with carboplatin (Paraplatin^®) or due to failure to differentiate daily dosages from total dosage per cycle. Cisplatin dosages >100 mg/m²/cycle once every 3–4 weeks rarely used.

Drug Info Tools

Pill Finder

Search by color, shape and markings. click here

Drug Interaction Checker

Check any 2 drugs for interactions. click here

Drug Compare

Compare any two drugs side by side. click here

Healthline Part D Plan Selector

Medicare's drug plans are subsidized by the US federal government and offered through insurers.

Marketplace

Licensed from

cisplatin

Page: 1 2 3 Next >

(siss PLAH tin)

What is the most important information I should know about cisplatin?

Cisplatin should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.

Serious side effects have been reported with the use of cisplatin including: allergic reactions (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); kidney damage (little or no urine production, blood in the urine); hearing loss or ringing in the ears; decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; or fever, chills, or signs of infection); severe nausea, vomiting, diarrhea, and loss of appetite; and others. Talk to your doctor about the possible side effects from treatment with cisplatin.

What is cisplatin?

Cisplatin is an antineoplastic medication. Cisplatin interferes with the growth of cancer cells and slows their growth and spread in the body.

Cisplatin is used to treat various types of cancer including metastatic testicular tumors, metastatic ovarian tumors, and advanced bladder cancer.

Cisplatin may also be used for purposes other than those listed in this medication guide.

Who should not use cisplatin?

Do not use cisplatin without first talking to your doctor if you have

kidney disease;
poor bone marrow function;
hearing impairment; or
an allergy to platinum or platinum-containing products.

The use of cisplatin may be dangerous if you have any of the conditions listed above.

Cisplatin is in the FDA pregnancy category D. This means that cisplatin is known to be harmful to an unborn baby. Do not use cisplatin without first talking to your doctor if you are pregnant. Discuss with your doctor the appropriate use of birth control during treatment with cisplatin if necessary. Cisplatin passes into breast milk and may harm a nursing baby. Breast-feeding should be avoided during treatment with cisplatin.

Page: 1 2 3 Next >