Drug Notebook

FDA Alerts

  • Use only under the supervision of a qualified clinician experienced in the use of cytotoxic therapy. Use only when adequate treatment facilities for appropriate management of therapy and complications are available.
  • Dose-related bone marrow suppression may result in infection and/or bleeding. Anemia may be cumulative and may require transfusion support.
  • Vomiting is a common adverse effect.
  • Anaphylactic-like reactions may occur within minutes of administration. Administer epinephrine, corticosteroids, and/or antihistamines to relieve symptoms.

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carboplatin
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(car bo PLAH tin)

What is the most important information I should know about carboplatin?

Carboplatin should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agents.

Serious side effects have been reported with the use of carboplatin including: allergic reactions (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); kidney damage (little or no urine production, blood in the urine); hearing loss or ringing in the ears; decreased bone marrow function and blood problems (extreme fatigue; easy bruising or bleeding; black, bloody or tarry stools; or fever, chills, or signs of infection); severe nausea, vomiting, diarrhea, and loss of appetite; and others. Talk to your doctor about the possible side effects from treatment with carboplatin.

What is carboplatin?

Carboplatin is an antineoplastic medication. Carboplatin interferes with the growth of cancer cells and slows their growth and spread in the body.

Carboplatin is used to treat ovarian cancer and many other types of cancer.

Carboplatin may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before using carboplatin?

Do not use carboplatin without first talking to your doctor if you have
  • kidney disease;
  • a bleeding problem;

  • poor bone marrow function;

  • hearing impairment; or

  • an allergy to platinum, platinum-containing products, or mannitol.

The use of carboplatin may be dangerous if you have any of the conditions listed above.

Carboplatin is in the FDA pregnancy category D. This means that carboplatin is known to be harmful to an unborn baby. Do not use carboplatin without first talking to your doctor if you are pregnant or could become pregnant during treatment. Discuss with your doctor the appropriate use of birth control during treatment with carboplatin if necessary. It is not known whether carboplatin passes into breast milk. Breast-feeding should be avoided during treatment with carboplatin.
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