• Basic Info
• Top Questions
• Clinical Info
• Interactions

Before receiving testosterone injection, tell your doctor if you are using any of the following drugs:

• the blood thinner warfarin (Coumadin);

• insulin or diabetes medication you take by mouth such as glimepiride (Amaryl, Duetact, Avandaryl), glipizide (Glucotrol), glyburide (Diabeta, Micronase, Glynase), metformin (Actoplus Met, Avandamet, Fortamet, Glucophage Janumet), rosiglitazone (Avandia), and others; or

• steroid medicine such as methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol), prednisone (Deltasone, Orasone, others), and others.

This list is not complete and there may be other drugs that can interact with testosterone injection. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• swelling, rapid weight gain;

• increased or ongoing erection of the penis;

• bone pain, increased thirst, memory problems, restless feeling, confusion, nausea, loss of appetite, increased urination, weakness, muscle twitching; or

• nausea, vomiting, stomach pain, loss of appetite, and jaundice (yellowing of the skin or eyes).

Women receiving testosterone injection may develop male characteristics, which could be irreversible if testosterone treatment is continued. Call your doctor as soon as possible if you notice any of these signs of excess testosterone:

• acne;

• changes in your menstrual periods;

• male-pattern hair growth (such as on the chin or chest);

• male pattern baldness;

• enlarged clitoris; or

• increase or decrease in sex drive.

Less serious side effects may include:

• breast swelling in men;

• headache, anxiety, depressed mood;

• numbness or tingly feeling; or

• pain or swelling where the medicine was injected.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.