• Basic Info
• Top Questions
• Clinical Info
• Interactions

Before taking amoxicillin, tell your doctor if you are using any of the following drugs:

• methotrexate (Rheumatrex, Trexall);

• probenecid (Benemid);

• a sulfa drug (such as Bactrim or Septra);

• an antibiotic such as azithromycin (Zithromax), clarithromycin (Biaxin), erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin), telithromycin (Ketek), or troleandomycin (Tao); or

• a tetracycline antibiotic such as demeclocycline (Declomycin), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap).

This list is not complete and there may be other drugs that can interact with amoxicillin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;

• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

• diarrhea that is watery or bloody;

• fever, chills, body aches, flu symptoms;

• easy bruising or bleeding, unusual weakness;

• urinating less than usual or not at all;

• agitation, confusion, unusual thoughts or behavior; or

• seizure (black-out or convulsions).

Less serious side effects are more likely to occur, such as:

• nausea, vomiting, stomach pain;

• vaginal itching or discharge;

• headache;

• swollen, black, or "hairy" tongue; or

• thrush (white patches or inside your mouth or throat).

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.