A narcotic analgesic - It is used to treat moderate to severe pain
FDA Alerts
Abuse Potential
Schedule II controlled substance with abuse liability similar to other opiates.
Potential for abuse in a manner similar to other legal or illicit opiates. Consider abuse potential when prescribing or dispensing morphine sulfate extended-release capsules (Kadian®) in situations where the clinician or pharmacist is concerned about increased risk of misuse, abuse, or diversion.
Overdose Risk with Improper Administration of Extended-release (Modified-, Controlled-, or Sustained-release) Products
Extended-release preparations (Avinza®, Kadian®, MS Contin®, Oramorph® SR) are indicated for relief of moderate to severe pain requiring continuous, around-the-clock opiate therapy for an extended period of time.
Extended-release formulations are to be swallowed whole; alternatively the contents of Avinza® or Kadian® capsules may be sprinkled on applesauce.
Extended-release capsules (e.g., Kadian®) are not intended for use as an as-needed (“prn”) analgesic.
Chewing, crushing, or dissolving any of these extended-release preparations (including capsule beads or pellets) could result in rapid release and absorption of a potentially fatal dose of morphine.
Do not consume alcoholic beverages or prescription or nonprescription preparations containing alcohol during therapy with extended-release capsules (Avinza®, Kadian®). Consuming alcohol while receiving extended-release capsules could result in rapid release and absorption of a potentially fatal dose of morphine.
This medicine is for injection as an epidural. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. This medicine is not approved for use in children.
Patients over 65 years old may have a stronger reaction and need a smaller dose.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
This does not apply.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
This medicine may also interact with the following medications:
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Your condition will be monitored carefully while you are receiving this medicine.
Tell your doctor or health care professional if your pain does not go away, if it gets worse, or if you have new or a different type of pain.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
This medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.
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