A narcotic analgesic - It is used to treat moderate to severe pain
FDA Alerts
Abuse Potential
Schedule II controlled substance with abuse liability similar to other opiates.
Potential for abuse in a manner similar to other legal or illicit opiates. Consider abuse potential when prescribing or dispensing morphine sulfate extended-release capsules (Kadian®) in situations where the clinician or pharmacist is concerned about increased risk of misuse, abuse, or diversion.
Overdose Risk with Improper Administration of Extended-release (Modified-, Controlled-, or Sustained-release) Products
Extended-release preparations (Avinza®, Kadian®, MS Contin®, Oramorph® SR) are indicated for relief of moderate to severe pain requiring continuous, around-the-clock opiate therapy for an extended period of time.
Extended-release formulations are to be swallowed whole; alternatively the contents of Avinza® or Kadian® capsules may be sprinkled on applesauce.
Extended-release capsules (e.g., Kadian®) are not intended for use as an as-needed (“prn”) analgesic.
Chewing, crushing, or dissolving any of these extended-release preparations (including capsule beads or pellets) could result in rapid release and absorption of a potentially fatal dose of morphine.
Do not consume alcoholic beverages or prescription or nonprescription preparations containing alcohol during therapy with extended-release capsules (Avinza®, Kadian®). Consuming alcohol while receiving extended-release capsules could result in rapid release and absorption of a potentially fatal dose of morphine.
Take this medicine by mouth with a glass of water. Do not break, crush, or chew the capsules. Do not take a capsule that is not whole. A broken or crushed capsule can be very dangerous. You may get too much medicine. If the medicine upsets your stomach, take the medicine with food or milk. If you have problems swallowing the capsule, you may carefully open it and sprinkle the contents on a small amount of cold applesauce. Immediately swallow all of the applesauce. Do not save it for later. Do not chew the applesauce. Do not let the medicine dissolve in the applesauce. Rinse your mouth with a sip of water. None of the medicine should stay in your mouth. Swallow all of the medicine. Follow the directions on the prescription label. Take the medicine at the same time each day. Do not take more medicine than you are told to take.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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