• Basic Info
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• Clinical Info

What is this medicine?

CHLORPROPAMIDE helps to treat type 2 diabetes. Treatment is combined with diet and exercise. This drug helps your body to use insulin better. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

• diabetic ketoacidosis
• glucose-6-phosphate dehydrogenase deficiency
• heart disease
• kidney disease
• liver disease
• porphyria
• severe infection or injury
• thyroid disease
• an unusual or allergic reaction to chlorpropamide, sulfonamides, other medicines, foods, dyes, or preservatives
• pregnant or trying to get pregnant
• breast-feeding

How should I use this medicine?

Take this medicine by mouth. Swallow with a drink of water. Follow the directions on the prescription label. If you take this medicine once a day, take it with breakfast. Take your medicine at the same time each day. Do not take more often than directed. Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed. Elderly patients over 65 years old may have a stronger reaction and need a smaller dose. Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

• bosentan
• chloramphenicol
• cisapride
• clarithromycin
• medicines for fungal or yeast infections
• metoclopramide
• probenecid
• warfarin

Many medications may cause an increase or decrease in blood sugar, these include:

• alcohol containing beverages
• aspirin and aspirin-like drugs
• chloramphenicol
• chromium
• female hormones, like estrogens or progestins and birth control pills
• heart medicines
• isoniazid
• male hormones or anabolic steroids
• medicines for weight loss
• medicines for allergies, asthma, cold, or cough
• medicines for mental problems
• medicines called MAO Inhibitors like Nardil, Parnate, Marplan, Eldepryl
• niacin
• NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
• pentamidine
• phenytoin
• probenecid
• quinolone antibiotics like ciprofloxacin, levofloxacin, ofloxacin
• some herbal dietary supplements
• steroid medicines like prednisone or cortisone
• thyroid medicine
• water pills or diuretics

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.