Vitamins Health Article

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Definition

Vitamins are organic components in food that are needed in very small amounts for growth and for maintaining good health. The vitamins include vitamins D, E, A, and K (fat-soluble vitamins), and folate (folic acid), vitamin B12, biotin, vitamin B6, niacin, thiamin, riboflavin, pantothenic acid, and vitamin C (ascorbic acid) (water-soluble vitamins). Vitamins are required in the diet in only tiny amounts, in contrast to the energy components of the diet. The energy components of the diet are sugars, starches, fats, and oils, and these occur in relatively large amounts in the diet.

Most of the vitamins are closely associated with a corresponding vitamin deficiency disease. Vitamin D deficiency causes rickets, a disease of the bones. Vitamin E deficiency occurs only very rarely and causes nerve damage. Vitamin A deficiency, common throughout the poorer parts of the world, causes night blindness. Severe vitamin A deficiency can result in xerophthalmia, a disease that, if left untreated, results in total blindness. Vitamin K deficiency results in spontaneous bleeding. Mild or moderate folate deficiency, common throughout the world, can result from the failure to eat green, leafy vegetables or fruits and fruit juices. Folate deficiency causes megaloblastic anemia, which is characterized by the presence of large abnormal cells called megaloblasts in the circulating blood. The symptoms of megaloblastic anemia are tiredness and weakness. Vitamin B12 deficiency occurs with the failure to consume meat, milk, or other dairy products. Vitamin B12 deficiency causes megaloblastic anemia and, if severe enough, can result in irreversible nerve damage. Niacin deficiency results in pellagra, which involves skin rashes and scabs, diarrhea, and mental depression. Thiamin deficiency results in beriberi, a disease resulting in atrophy, weakness of the legs, nerve damage, and heart failure. Vitamin C deficiency results in scurvy, a disease that involves bleeding. Diseases associated with deficiencies in vitamin B6, riboflavin, or pantothenic acid have not been found in the humans, though persons who have been starving or consuming poor diets for several months, might be expected to be deficient in most of the nutrients, including vitamin B6, riboflavin, and pantothenic acid. Rarely, deficiency in B6 results in neurologic problems. Issues of toxicity are connected to the over consumptions of vitamins, particularly E, K, and B. Also, lack of regulation in the vitamin industry means consumers ought only to buy well-known brands.

Some of the vitamins serve only one function in the body, while other vitamins serve a variety of unrelated functions. Hence, some vitamin deficiencies tend to result in one type of defect, while other deficiencies result in a variety of problems.

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Author Info: L. Fleming Fallon Jr., MD, DrPH, Thomson Gale, Gale, Detroit, Gale Encyclopedia of Children's Health, 2006
 
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