Temazepam Health Article

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Definition

Temazepam is a drug that belongs to a family of drugs known as benzodiazepines. Temazepam is sold under the brand name Restoril in the United States. Temazepam is also available as a generic.

Purpose

Temazepam is given to patients with sleeping problems (insomnia). It is often prescribed for insomnia characterized by frequent awakening during the night or by awakening early in the morning.

Description

Temazepam is one of several drugs in the class known as benzodiazepines. These drugs produce a variety of effects, but most cause some degree of drowsiness (sedation). Temazepam is used almost exclusively as a hypnotic, or drug given to help people fall asleep. It is nearly always taken just before bedtime. This drug produces its effects in the body by slowing down certain impulses in the brain, allowing the patient to fall asleep.

Recommended dosage

The typical dose starting for adults is 7.5–15 mg taken just before bedtime. The maximum recommended dose is 30 mg. Elderly patients and those in a weakened condition may need only 7.5 mg. The doctor should determine the dose in children 18 years of age and younger on an individual basis.

Precautions

The doctor should monitor any patient taking this drug to ensure that significant side effects do not develop. Insomnia that lasts longer than seven to 10 days may point to a significant medical problem that should be thoroughly evaluated. Temazepam should not be combined with alcohol or other drugs that lower the level of activity in the central nervous system. Examples of such drugs include prescription pain medications, antihistamines, barbiturates, and muscle relaxants. Some people may develop dizziness, lightheadedness, and clumsiness after taking temazepam. These side effects are especially common in the elderly.

Those with a history of anemia, liver disease, kidney disease, drug abuse, serious psychological disorders, and suicide attempts should be given temazepam only after being thoroughly evaluated by their physician. This caution also applies to persons with a history of lung disease, seizure disorders, and narrow-angle glaucoma.

People who are taking temazepam should not stop taking it abruptly. Instead, the dose should be reduced gradually. Withdrawal symptoms, including depressed mood, sweating, abdominal cramps, muscle cramps, vomiting, seizures, and shakiness can develop if the medication is stopped suddenly.

Although patients are instructed to take temazepam in the evening before bedtime, they often experience side effects the next day, particularly drowsiness and loss of coordination or clumsiness. Pregnant women should not use this drug because it increases the risk of birth defects in the baby. Nursing mothers should not be given temazepam because it can make their babies drowsy and unable to nurse properly. Patients should not operate heavy machinery or drive a car while they are taking temazepam or any other benzodiazepine.

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Author Info: Mark Mitchell M.D., The Gale Group Inc., Gale, Detroit, Gale Encyclopedia of Mental Disorders, 2003
 
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