Diazepam Health Article

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Definition

Diazepam is a mild tranquilizer in the class of drugs known as benzodiazepines. It is most commonly sold in the United States under the brand name Valium. The generic form of this drug is also available.

Purpose

Diazepam is used on a short-term basis to treat patients with mild to moderate anxiety. It is also used to treat some types of seizures (epilepsy), muscle spasms, nervous tension, and symptoms relating to alcohol withdrawal.

Description

Diazepam is one of many chemically-related tranquilizers in the class of drugs called benzodiazepines. Benzodiazepines are sedative-hypnotic drugs that help to relieve nervousness, tension, and other anxiety symptoms by slowing the central nervous system. To do this, they block the effects of a specific chemical involved in the transmission of nerve impulses in the brain, decreasing the excitement level of the nerve cells. All benzodiazepines, including diazepam, cause sedation, drowsiness, and reduced mental and physical alertness.

Recommended dosage

The typical dose of diazepam used to treat anxiety or seizures in healthy adults ranges from a total of 6 milligrams (mg) to 40 mg per day given in three or four doses. Elderly people (over age 60) are usually given lower doses in the range of 4–10 mg per day to treat anxiety or nervous tension. For acute treatment of seizures, a higher dose of diazepam is given intravenously (directly into the vein) only in a controlled medical setting such as a hospital or emergency room. For alcohol withdrawal, the typical dose is a total of 30–40 mg per day given in three or four doses.

The typical dose for a child over age six months with anxiety or seizures is a total of 3–10 mg per divided into several doses. In general, children receive lower doses of diazepam even when they have a body weight equivalent to a small adult. Diazepam is usually taken as a pill, but an injectable form is sometimes used when a serious seizure is in progress or when muscle spasms are severe. There is also a liquid oral form of the drug available.

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Author Info: Mark Mitchell M.D., The Gale Group Inc., Gale, Detroit, Gale Encyclopedia of Mental Disorders, 2003
 
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