Brain Tumor Health Article

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Definition

A brain tumor is an abnormal growth of tissue in the brain. Unlike other tumors, brain tumors spread by local extension and rarely metastasize (spread) outside the brain. A benign brain tumor is composed of non-cancerous cells and does not metastasize beyond the part of the brain where it originates. A brain tumor is considered malignant if it contains cancer cells, or if it is composed of harmless cells located in an area where it suppresses one or more vital functions.

Description

Each year, more than 17,000 brain tumors are diagnosed in the United States. About half of all primary brain tumors are benign, but in life-threatening locations. The rest are malignant and invasive.

Benign brain tumors

Benign brain tumors, composed of harmless cells, have clearly defined borders, can usually be completely removed, and are unlikely to recur. Benign brain tumors do not infiltrate nearby tissues but can cause severe pain, permanent brain damage, and death. Benign brain tumors sometimes become malignant.

Malignant brain tumors

Malignant brain tumors do not have distinct borders. They tend to grow rapidly, increasing pressure within the brain (IICP) and can spread in the brain or spinal cord beyond the point where they originate. It is highly unusual for malignant brain tumors to spread beyond the central nervous system (CNS).

Primary brain tumors

Primary brain tumors originate in the brain. They represent about 1% of all cancers and 2.5% of all cancer deaths.

Metastatic or secondary brain tumors

Approximately 25% of all cancer patients develop secondary or metastatic brain tumors when cancer cells spread from another part of the body to the brain. Secondary brain tumors are most apt to occur in patients who have:

  • breast cancer.
  • colon cancer.
  • kidney cancer.
  • lung cancer.
  • melanoma (cancer) of the skin. These metastatic brain tumors can develop on any part of the brain or spinal cord.
  • cancer within the nasal passages and/or throat that follow the nerve pathways into the skull, and metastasize to the brain.
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Author Info: Rosalyn Carson-DeWitt M.D., The Gale Group Inc., Gale, Detroit, Gale Encyclopedia of Medicine, 2002
 
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