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Pernicious anemia is caused by a lack of intrinsic factor. Intrinsic factor is a protein produced by the stomach that helps the body absorb vitamin B12. When stomach does not have enough intrinsic factor, it cannot properly absorb the vitamin. Ner...
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Pernicious anemia is a disease in which the red blood cells are abnormally formed, due to an inability to absorb vitamin B 12 . True pernicious anemia refers specifically to a disorder of atrophied parietal cells leading to absent intrinsic factor...
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Intrinsic factor is a natural substance normally present in the stomach. It is essential to the digestion of vitamin B-12. Lack of intrinsic factor leads to pernicious anemia and vitamin B-12 deficiency. Babies that are born without intrinsic factor cannot properly absorb vitamin B-12 starting around 6 months of age. The juvenile type of lack of intrinsic factor tends to manifest itself after the age of ten.
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