Metachromatic Leukodystrophy : Tests

Signs include: Decreased or absent deep tendon reflexes; Abnormal eye movements; Poor visual fixation; Optic nerve atrophy; Posture abnormalities; Coma. Possible tests include: Nerve velocity conduction studies; MRI; CT scan; Lumbar puncture; Nerv...

Metachromatic leukodystrophy (MLD) is a rare degenerative neurological disease, and is the most common form of the leukodystrophies, a group of disorders affecting the fatty covering that acts as an insulator around nerve fibers known as the myeli...

During a physical examination, a health care provider studies a patient's body to determine the presence or absence of physical problems. A typical physical examination includes: Inspection (looking at the body; Palpation (feeling the body with hands; Auscultation (listening to sounds; Percussion (producing sounds.

An MRI of the head is a noninvasive procedure that uses powerful magnets and radio waves to construct clear, detailed pictures of brain tissues. Conventional radiography and computed tomographic (CT) imaging use potentially harmful radiation (x-rays) that passes through a patient to generate images. Magnetic resonance imaging (MRI) is based on the magnetic properties of atoms, and there is no exposure to the same type of radiation used in x-rays and CT scans. A powerful magnet generates a magnetic field roughly 10,000 times stronger than the Earth's. A very small percentage of hydrogen atoms within the body will align with this field. Radio wave pulses are broadcast towards the aligned hydrogen atoms in tissues of interest, returning a signal of their own. The slight differences of those signals from different tissues enables MRI to tell the difference between various organs, and potentially, provide contrast between benign and malignant tissue. Any imaging angle, or "slice", can be projected, and then stored in a computer or printed on film. MRI can easily be performed through clothing and bones. However, certain types of metal in or around the area of interest can cause significant errors in the reconstructed images. These errors are called artifacts.

Part of the central nervous system located in the skull. Controls mental and physical actions of the organism.

Congenital brain defects are a group of disorders of brain development that are present at birth. Brain development begins shortly after conception and continues throughout the growth of a fetus.

Brain abscess is a bacterial infection within the brain. The brain is usually well insulated from infection by bacteria, protected by the skull, the meninges (tissue layers surrounding the brain), the immune system, and the highly regulated barrier between the bloodstream and the brain.

A brain biopsy is the removal of a small piece of brain tissue for the diagnosis of abnormalities of the brain, such as Alzheimer ' s disease , tumors, infection, or inflammation. Purpose By examining the tissue sample under a microscope, the biopsy sample provides doctors with the information necessary to guide diagnosis and treatment.

A brain tumor is an abnormal growth of tissue in the brain. Unlike other tumors, brain tumors spread by local extension and rarely metastasize (spread) outside the brain.

The brain is the part of the central nervous system located in the skull. It controls the mental processes and physical actions of a human being.

The brain is a large mass of soft nervous tissue made up of both neurons and supporting glial cells lying within the cranium of the skull. The brain contains both gray and white matter.

Magnetic resonance imaging (MRI) scanners rely on the principles of atomic nuclear-spin resonance. Using strong magnetic fields and radio waves, MRI collects and correlates deflections caused by atoms into images.

Traumatic brain injury (TBI) is the result of physical trauma to the head causing damage to the brain. This damage can be focal, or restricted to a single area of the brain, or diffuse, affecting more than one region of the brain.

The brain is the part of the central nervous system (CNS) inside the skull (the part outside the skull is the spinal cord ). It gives rise to cognitive thought processes and controls various body functions including muscular activity, speech, sight, hearing , breathing, and digestion.

A brain tumor is an abnormal growth of tissue, either malignant (cancerous) or benign (noncancerous), in the brain. Each year, more than 17,000 brain tumors are diagnosed in the United States.

Like all other parts of the body, the brain and central nervous system are made up of cells that ordinarily grow and divide to create new cells as needed. This is usually an orderly process; but when cells lose their ability to grow normally or to die off naturally, they divide too often and produce tumors that are made up of these extra cells.

Congenital brain defects are a group of disorders of brain development. Brain development begins shortly after conception and continues throughout the growth of a fetus.

A nerve conduction study is a test that measures the movement of an impulse through a nerve after the deliberate stimulation of the nerve. Purpose The ability of a nerve to swiftly and properly transmit an impulse down its length, and to pass on the impulse to the adjacent nerve or to a connection muscle in which it is embedded, is vital to the performance of many activities in the body.

EMG and NCS TestsElectromyography(EMG)and nerve conduction studies(NCS)are tests that measure muscle and nerve function. In most cases, both tests are performed.