Constipation : Supplements

Transparent gel from the pulp of the meaty leaves of Aloe vera has been used topically for thousands of years to treat wounds, skin infections, burns, and numerous other dermatologic conditions. Dried latex from the inner lining of the leaf has traditionally been used as an oral laxative. There is strong scientific evidence in support of the laxative properties of aloe latex, based on the well-established cathartic properties of anthroquinone glycosides (found in aloe latex). However, aloe's therapeutic value compared with other approaches to constipation remains unclear. There is promising preliminary support from laboratory, animal, and human studies that topical aloe gel has immunomodulatory properties which may improve wound healing and skin inflammation.

Appearance Aloe vera , a member of the lily family, is a spiky, succulent, perennial plant. It is indigenous to eastern and southern Africa, but has been spread throughout many of the warmer regions of the world, and is also popularly grown indoors.

Cascara is obtained from the dried bark of Rhamnus purshianus (Rhamnaceae), both a medicinal and poisonous plant. It is found in Europe, western Asia, and in North America from northern Idaho to the Pacific coast in mountainous areas. In Spanish, cascara sagrada means "sacred bark," perhaps because this woody shrub has provided relief for several constipated individuals. Cascara has been used as a tree bark laxative by Native American tribes and Spanish and Mexican priests since the 1800s. The cascara sagrada bark is aged for a year so that the active principles become milder, as freshly dried bark produces too strong a laxative for safe use. Cascara possesses purgative, toxic, therapeutic, and tonic activity. It is most commonly used as an anthraquinone stimulant laxative for bowel cleansing. Stimulant and cathartic laxatives are the most commonly abused laxatives and have the potential for causing long-term damage.

Phosphorus is a mineral found in many foods, such as milk, cheese, dried beans, peas, colas, nuts, and peanut butter. Phosphate is the most common form of phosphorus. In the body, phosphate is the most abundant intracellular anion. It is critical for energy storage and metabolism, for the utilization of many B-complex vitamins, to buffer body fluids, for kidney excretion of hydrogen ions, for proper muscle and nerve function, and for maintaining calcium balance. Phosphorus is vital to the formation of bones and teeth, and healthy bones and soft tissues require calcium and phosphorus to grow and develop throughout life. Inadequate intake of dietary phosphate can lead to hypophosphatemia (low levels of phosphate in the blood), which can lead to long-term potentially serious complications. Conversely, excess phosphate intake can lead to hyperphosphatemia (high blood phosphorus levels), which can occur particularly in people with impaired kidney function, and can lead to potentially serious electrolyte imbalances, adverse effects, or death. In adults, phosphorus makes up approximately 1% of total body weight It is present in every cell of the body, although 85% of the body's phosphorus is found in the bones and teeth. Phosphates are used clinically to treat hypophosphatemia, hypercalcemia (high blood calcium levels), as saline laxatives, and in the management of calcium-based kidney stones. They may also be of some benefit to patients with vitamin D resistant rickets, multiple sclerosis, and diabetic ketoacidosis.

Phosphorus (chemical symbol P) is a mineral discovered by the German alchemist Henig Brand in 1699. It plays an essential part in multiple biochemical reactions for both plants and animals and is essential to all life.

Phosphorus (chemical symbol P) is a mineral discovered by the German alchemist Henig Brand in 1699. It plays an essential part in multiple biochemical reactions for both plants and animals and is essential to all life.

Psyllium, also referred to as ispaghula, is derived from the husks of the seeds of Plantago ovata . Psyllium contains a high level of soluble dietary fiber, and is the chief ingredient in many commonly used bulk laxatives, including products such as Metamucil® and Serutan®. Psyllium has been studied as a "non-systemic" cholesterol-lowering agent, with generally modest effects seen on total cholesterol and low-density lipoprotein levels. Several psyllium-containing cereals such as Heartwise® and Bran Buds® have appeared in the United States marketplace during the last 15 years, and have been touted for their potential lipid lowering and "heart health promoting" effects. Allergic reactions, including anaphylaxis have been reported, particularly in healthcare workers with previous experience preparing psyllium-containing bulk laxatives. Obstruction of the gastrointestinal tract by such laxatives has also been reported, particularly in patients with prior bowel surgeries or anatomic abnormalities, or when mixed with inadequate amounts of water.

Cellulose derivatives (methylcellulose), calcium polycarbophil, malt soup extract, and psyllium preparations are bulk-forming laxatives.

Psyllium is a seed used for medicinal purposes taken from the common fleawort, Plantago psyllium . There are about 250 species of the genus Plantago found worldwide; they belong to the Plantaginaceae family.

Chinese herbalists have relied on rhubarb rhizomes and roots for thousands of years. The rhizomes and roots contain powerful anthraquinones and tannins that act as stimulant laxatives and astringents, respectively. In traditional Chinese medicine, rhubarb is also used to treat gastric ulcers, chronic renal (kidney) failure, and pregnancy-induced hypertension (high blood pressure), pre-eclampsia and eclampsia. European herbalists have recommended rhubarb as a laxative, diuretic, and to treat kidney stones, gout (foot inflammation), and liver diseases. Externally, it is recommended to heal skin sores and scabs. The current practice of using rhubarb to treat cancer (as an ingredient in the herbal Essiac® formula) lacks the support of controlled clinical trials. However, rhubarb is being tested for multiple other conditions, including hyperlipidemia (high cholesterol) and obesity. Use for gingivitis, chronic renal failure and upper gastrointestinal bleeding seem to be the most promising, although more research should be done in these areas, specifically with rhubarb as a monotherapy.

Rhubarb, also called sweet round-leaved dock or pieplant, is usually thought of as a fruit, but it is actually one of the few perennial vegetables in existence. Ordinary garden rhubarb carries the botanical name of Rheum rhaponticum , though there are other members of this botanical group that are also used for medicinal purposes.