Alcohol Withdrawal Syndrome : Supplements

5-HTP is the precursor of the neurotransmitter serotonin. It is obtained commercially from the seeds of the plant Griffonia simplicifolia . 5-HTP has been suggested as a treatment for many conditions. There is some research to support the use of 5-HTP in treating cerebellar ataxia, headache, depression, psychiatric disorders, fibromyalgia and as an appetite suppressant or weight-loss agent. There is not enough scientific evidence to support the use of 5-HTP for any other medical condition. 5-HTP may cause gastrointestinal disturbances, mood disturbances, seizure or abnormal blood counts. Some reported side effects might result from contaminants in 5-HTP products. There has been recent interest in the use of 5-HTP as a precursor therapeutic agent to increase serotonin production. 5-HTP has replaced tryptophan, which was previously used in that role, but has been linked to serious adverse effects. 5-HTP has orphan drug status for the treatment of post-anoxic myoclonus (Lance-Adams syndrome), a rare complication of successful cardiopulmonary resuscitation.

The acronym for 5-hydroxytryptophan (or 5-hydroxy-L-tryptophan) is 5-HTP, a compound found primarily in the brain. This compound is made from tryptophan, a natural amino acid inherent in foods.