MIBG scintiscan Health Article

Definition

MIBG scintiscan is a nuclear scan test that uses injected radioactive material (radioisotope) and a special scanner to locate or confirm the presence of pheochromocytoma and neuroblastoma, which are tumors of specific types of nervous tissue.

Alternative Names

Adrenal medullary imaging; Meta-iodobenzylguanidine scintiscan

How the test is performed

A radioisotope (MIBG, iodine-131-meta-iodobenzylguanidine) is injected into a vein. This compound attaches to specific tumor cells.

Later that day (or the next day) you lie on a table that is positioned under the arm of the scanner. The abdomen is scanned. You may be asked to return for repeated scans for 1 - 3 days. Each scan takes 1 - 2 hours.

Before or during the test, you may be given an iodine solution to prevent the thyroid from absorbing too much of the radioisotope.

How to prepare for the test

You must sign an informed consent form. You will be asked to wear a hospital gown. However, loose-fitting clothing may be allowed. Remove jewelry or metal objects before each scan.

How the test will feel

There is a sharp needle prick when the material is injected. The table may be cold or hard. You must lie still during the scan.

Why the test is performed

This test is done to confirm pheochromocytoma or neuroblastoma.

Normal Values

There are no signs of a tumor.

What abnormal results mean

Most often, this test is used to locate pheochromocytoma. It may be very useful to detect multiple tumors or tumors that are located outside the adrenal tissues.

Additional conditions under which the test may be performed include multiple endocrine neoplasia (MEN II