Hodgkin's lymphoma Health Article

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Definition

Hodgkin's lymphoma is a malignancy (cancer) of lymph tissue found in the lymph nodes, spleen, liver, and bone marrow.

Alternative Names

Lymphoma - Hodgkin's; Hodgkin's disease; Cancer - Hodgkin's lymphoma

Causes, incidence, and risk factors

The first sign of this cancer is often an enlarged lymph node which appears without a known cause. The disease can spread to nearby lymph nodes and later may spread to the lungs, liver, or bone marrow.

The cause is not known. Hodgkin's lymphoma is most common among people 15 to 35 and 50 to 70 years old.

Symptoms

Additional symptoms that may be associated with this disease:

Signs and tests

The disease may be diagnosed after:

A staging evaluation (tumor staging) may be done to determine the extent of the disease. The following procedures may be done:

In some cases, abdominal surgery to take a piece of the liver and remove the spleen may be needed. However, because the other tests are now so good at detecting the spread of Hodgkin's lymphoma, this surgery is usually unnecessary.

Hodgkin's lymphoma may change the results of the following tests:

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Reviewer Info: William Matsui, MD, Assistant Professor of Oncology, Division of Hematologic Malignancies, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD. Review provided by VeriMed Healthcare Network.; ADAM Health Illustrated Encyclopedia, 05/03/2006
 
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