Atrial myxoma Health Article

Definition

An atrial myxoma is a noncancerous tumor in the upper left or right side of the heart. It grows on the wall (atrial septum) that separates the two sides of the heart.

Causes, incidence, and risk factors

A myxoma is a primary heart (cardiac) tumor. This means that the tumor started within the heart. Most heart tumors start somewhere else.

Primary cardiac tumors are rare. Myxomas are the most common type of these rare tumors. About 75% of myxomas occur in the left atrium of the heart, usually beginning in the wall that divides the two upper chambers of the heart. The rest are in the right atrium. Right atrial myxomas are sometimes associated with tricuspid stenosis and atrial fibrillation.

Myxomas are more common in women. About 10% of myxomas are passed down through families (inherited). Such tumors are called familial myxomas. They tend to occur in more than one part of the heart at a time, and often cause symptoms at a younger age than other myxomas.

Symptoms

Symptoms may occur at any time, but most often they accompany a change of body position. Symptoms may include:

• Breathing difficulty when lying flat
• Breathing difficulty when asleep
• Chest pain or tightness
• Dizziness
• Fainting
• Sensation of feeling your heart beat (palpitations)
• Shortness of breath with activity

The symptoms and signs of left atrial myxomas often mimic mitral stenosis

General symptoms may also be present, such as:

• Blueness of skin, especially the fingers (Raynaud's phenomenon)
• Cough
• Curvature of nails accompanied with soft tissue enlargement (clubbing) of the fingers
• Fever
• Fingers that change color upon pressure or with cold or stress
• General discomfort (malaise)
• Involuntary weight loss
• Joint pain
• Swelling - any part of the body

These general symptoms may also mimic those of infective endocarditis.